Monoclonal antibodies to Nocardia asteroides and Nocardia brasiliensis antigens
نویسندگان
چکیده
منابع مشابه
Nocardia asteroides osteomyelitis.
Nocardia asteroides osteomyelitis has previously been described only in acutely ill patients. It may occur as an isolated event or part of the disease spectrum of disseminated nocardiosis. An 84 year old immune competent man with N. asteroides right tibial osteomyelitis had an unusual presentation, presumed mechanism of disease and outcome. His course affords an opportunity to review the litera...
متن کاملNocardia asteroides ocular infection
Methods The ocular samples viz., corneal swab, corneal scraping, aqueous tap and vitreous tap were processed for culture and the isolated Nocardia species were further confirmed for speciation by standard microbiological procedures. Antibiotic susceptibility analysis for the confirmed isolates of N. asteroides was performed by agar disk diffusion method following the guidelines of Clinical Labo...
متن کامل[Nocardia asteroides keratitis].
Problems in management of ulcerative keratitis may arise from delays in diagnosis and from inadequate response to treatment. In the present case, a corneal injury was followed by Nocardia asteroides keratitis. The organism isolated was sensitive in vitro to both sulphonamides and penicillin, but there was no satisfactory clinical improvement with sulphonamides alone. Good response to treatment ...
متن کاملNocardia asteroides keratitis.
Nocardia asteroides has been reported as the cause of keratitis in only 7 cases and of other ocular disease in another 12 cases. We report a case of N. asteroides keratitis that presented 3 weeks after rural trauma and progressed despite trials of appropriate antibiotics. Seven weeks after the origianl injury a successful conjunctival flap was placed over the cornea. The morphology and the sens...
متن کاملMonoclonal antibodies demonstrate that superoxide dismutase contributes to protection of Nocardia asteroides within the intact host.
The importance of superoxide dismutase (SOD) in protecting cells of Nocardia asteroides from the oxidative killing mechanisms within the intact murine host was determined. Murine monoclonal antibodies specific for nocardial SOD and for another nocardial antigen were prepared. Both antibodies adhered to cell surface antigens, as shown by fluorescence-labeled-antibody staining. The anti-nocardial...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 1990
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.28.1.87-91.1990